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In addition, hypoxia represents an inhibitory signal for GSH synthesis, since it decreases the activity of the two key biosynthetic enzymes GCL and GS [13]

PMID: 38797248 10 Vitamin B12 deficiency in the elderly: is it worth screening

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Some of protective substances have the ability to reduce BaP metabolism, and in particular reduce the induction of cytochrome (CYP P450), which reduces the formation of oxidative metabolites, and therefore decreases ROS production
