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[4] [11] This mechanism becomes clinically relevant when treating pernicious anaemia or intrinsic factor deficiency with high-dose oral supplementation

By replenishing B12 stores, it ensures that key bodily processes, including nerve function and cellular energy metabolism, operate effectively

Candidates were excluded if they had a history of a neurological disorder that may better explain the results of the study such as epilepsy, brain trauma, neuropsychiatric disorder or mild cognitive impairment

Studies discovered mitochondrial-derived peptide called MOTS-c has been shown to significantly reduce the level of pro-inflammatory factors in mice and increase anti-inflammatory factors and insulin-stimulated glucose treatment rates, as well as glucose homeostasis (79)
