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Lipofuscin is a chromophore that serves as a primary RPE photo-oxide [28], which, after absorbing high energy photons (especially blue light), undergoes a series of photochemical reactions

Cell-based therapies, including CAR T-cell therapy and stem cell transplantation, showed early promise in refractory disease but remain limited by safety concerns and insufficient long-term data

Our orientation analyses indicate that WT -SNAP closely matches this arrangement, whereas M105I favors a horizontally biased conformation that is incompatible with symmetric positioning of -SNAP around the SNARE bundle

Some people notice changes within hours, while others see the full effect build over several weekly sessions