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In PD patients, nearly 80% loss of CP ferroxidase activity in the SN may lead to pro-oxidative iron accumulation, as evidenced by CP knockout mice developing parkinsonian symptoms reversible by iron chelation (56)
Silvestro S, Raffaele I, Quartarone A, Mazzon E
3b) [87]
CD8 + T cells were activated and treated with ML226 for 11 days, as previously described, incubated at 21%, 5% or 1% oxygen for 2 h, and then reactivated with anti-CD3/CD28 Dynabeads
