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Elevated expression of liver de novo serine synthesis pathway enzymes, phosphoglycerate dehydrogenase (PHGDH) and phosphoserine aminotransferase 1 (PSAT1), is among the most reproducible responses to dietary SAAR, making their increase a marker of a successful dietary intervention (2

The same guidance applies to breastfeeding mothers: biotin in normal dietary amounts is safe and necessary, but megadoses are not recommended without medical indication

After the imaging, the cells were trypsinised, re-suspended in the complete media, and relative number of living cells were counted by using Countess II after staining with trypan blue

[DOI] [PubMed] [Google Scholar] 200.Ito T, Ikeda U, Shimpo M, Yamamoto K and Shimada K