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Accidental cell death occurs in response to severe physical, chemical and mechanical insults and cannot be reversed by molecular signaling pathways ( Ferroptosis Ferroptosis is defined as iron-dependent programmed cell death that is different from traditional cell death processes, such as apoptosis and autophagy

Mechanically, artesunate upregulated the expression of autophagy-associated proteins and inhibited the expression of FTH1 and NCOA4, indicating that ferritinophagy-mediated ferroptosis in HSCs is crucial in the antifibrotic therapy of artesunate (Kong et al., 2019)

[30] For humans, and for animals that have consumed either the rodenticide or rats poisoned by the rodenticide, treatment is prolonged administration of large amounts of vitamin K