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This trend is also noticeable when comparing the panels in Supplemental Figure 2 as well as between Figure 9 and Supplemental Figures 35, where most of the original clusters shown in blue remain constant throughout the 4 figures, while the ones that become significant are depicted mainly as red or purple, reflecting a shift from hypometabolism of significant metabolites toward hypermetabolism for newly significantly different metabolites
CIPN can limit the dosages and choices of drugs, and in serious cases, it leads to discontinuation of treatment
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Results build gradually, and a course of sessions is often needed for a clear change
