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Within the CNS, PACAP is expressed primarily by nuclei of the brainstem, hypothalamus and thalamus, amygdala, cerebral cortex, medulla oblongata, and posterior pituitary as a 178-amino acid preprohormone

Hydrating Lip Balm : Use a lip balm with shea butter or hyaluronic acid to keep your lips hydrated and protected from dryness and cracking

Monitoring for symptoms and consulting a healthcare provider is important, especially for older adults or those with liver, kidney, or GI issues

If 10 mg produces excellent efficacy but borderline intolerable nausea, try 7.5 mg for 6 to 8 weeks to assess whether efficacy remains adequate with improved tolerability