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If you have any doubts about whether the medication has been stored properly or if it was left at room temperature for an extended time, contact the pharmacy or your healthcare provider for advice

The dermis is starting to retain more moisture as glycosaminoglycan synthesis ramps up

Patients using metformin for prolonged periods may, therefore, need initial screening with intermittent follow-up, particularly since vitamin B 12 deficiency has similar symptoms to diabetic neuropathy which itself affects 40 50% of patients with T2DM at some stage

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