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Emergency dermatology Medicine
While tirzepatide does not directly affect B12 absorption like metformin, reduced intake of animal productscommon during appetite suppressionmay lead to inadequate B12 levels
Additionally, the Pcca -/- (A138T) mouse model, representing one of the gene mutations observed in human patients with a milder phenotype 38,49,56,57 , may not fully recapitulate the diverse conditions (various genotypes, disease severity, and metabolic crises) encountered in human PA patients
Patients with OTC deficiency can have unexplained seizures, vomiting, headaches, abnormal behavior, and lethargy
