isobutyryl-l-carnitine Illustration of isobutyrylcarnitine metabolism. Oxidation of Carnitine is often chosen by individuals looking to complement their nutrition and fitness programs L-Carnitine - Arazo Nutrition
Description
When the remaining 80% of the l-carnitine supplement arrives in the colon, the microbes start absorbing the nutrient and they use it to produce something else: trimethylamine (TMA)

Acetyl L-Carnitine can cross the blood-brain barrier effectively due to its acetylated form, which makes the molecule more lipophilic (fat-soluble)

FEMS Microbiol Rev 42:656671

Rankovic A
