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From the standpoint of economic efficiency, the reproductive ability of domestic food animals such as sheep is the most critical trait that may be compromised by climate stressors 8

10.1038/s41593-018-0332-9 53 Farshbaf-KhaliliA.OstadrahimiA.MirghafourvandM.Ataei-AlmanghadimK.DoustiS.IranshahiA

However accumulated evidence now clearly suggests that PGHS-2 is also constitutively expressed in a number of tissues including brain, gut, lung, thymus and kidney wherein it produces prostanoids [97]