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Description
The Novel Dihydroorotate Dehydrogenase (DHODH) Inhibitor PTC299 Inhibit De Novo Pyrimidine Synthesis with Broad Anti-Leukemic Activity Against Acute Myeloid Leukemia
Supplementing with reduced glutathione supports this critical bottleneck, ensuring toxins can be safely packaged and removed
10.1513/pats.200512-125SF Proc Am Thorac Soc
Rijken et al., 2011)
