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In parallel, dysfunction of cytoplasmic Pattern Recognition Receptors (PRRs) (e.g., retinoic acid-inducible gene I) impairs downstream type I interferon (IFN-I) signalling, resulting in diminished phagocytic capacity and blunted IFN-I responses [48]
[1] This yields a relatively non-toxic metabolite, which is excreted into bile and passed out of the body
were the first to have used C
