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Overall, the overload of oxidized substrates together with the oxidative damage to proteasome lead to the accumulation of abnormal proteins and to selective degeneration of neurons, which characterize the AD condition (FIGURE 10)

[DOI] [PubMed] [Google Scholar] Koob GF (2011) Theoretical frameworks and mechanistic aspects of alcohol addiction: alcohol addiction as a reward deficit disorder

Baicalin inhibits IL-17-mediated joint inflammation in murine adjuvant-induced arthritis
