what if glutathione s transferase impaired supplementation Overexpression of S-Transferases in Human Diseases: Drug Targets and Therapeutic Implications Microsomal glutathione transferase 1 controls

Description

Withania Somnifera - an Indian plant, whose function is based on strengthening the body's overall immunity, as well as increasing the threshold of stress

Abbreviations AGAT II Alanine-glyoxylate aminotransferase isoenzyme II AlaAT Alanine aminotransferase ANIT 1-Naphthylisothiocyanate AOA Aminooxyacetate APN Aminopeptidase N AspAT Aspartate aminotransferase BCAT c Cytosolic branched-chain amino acid aminotransferase BCAT m Mitochondrial branched-chain amino acid aminotransferase BCKADHC Branched-chain keto acid dehydrogenase complex BTC S -(2-Benzothiazolyl)-l-cysteine CCBL1 Cysteine conjugate -lyase 1 CCBL2 Cysteine conjugate -lyase 2 Cyt Cytosolic DCVC S -(1,2-Dichlorovinyl)-l-cysteine DCVHC S -(1,2-Dichlorovinyl)-l-homocysteine FMO Flavin-dependent monooxygenase GGT -Glutamyltransferase GSH Glutathione (-glutamylcysteinylglycine) GST Glutathione S -transferase GTK Glutamine transaminase K GTL Glutamine transaminase L KAT Kynurenine aminotransferase KGDHC -Ketoglutarate dehydrogenase complex KMB -Keto--methiolbutyrate Mit Mitochondrial PCBC S -(1,2,3,4,4-Pentachloro-1,3-butadienyl)-l-cysteine PD Parkinson disease PDHC Pyruvate dehydrogenase complex PG Prostaglandin PLP Pyridoxal 5-phosphate PMP Pyridoxamine 5-phosphate rhGTK Recombinant human GTK TCA Tricarboxylic acid TCVC S -(1,2,2-Trichlorovinyl)-l-cysteine TFEC S -(1,1,2,2-Tetrafluoroethyl)-l-cysteine THT Tetrahydrothiophene THT-A -( S -Tetrahydrothiophenium)-l-alanine UTR Untranslated region References Abel E.L., Lyon R.P., Bammler T.K., Verlinde C.L., Lau S.S., Monks T.J., Eaton D.L

If glutathione levels become excessively high, it could theoretically influence immune function, possibly leading to an imbalance favoring yeast overgrowth