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Clean the injection site with an alcohol swab Insert the needle at a 90-degree angle Aspirate to check for blood Inject the medication slowly Managing Pain During Intramuscular Injections To lessen pain during HCG injections, try these tips: Relax the muscle before injection Use a sharp needle Inject slowly Apply gentle pressure after injection Self-Administration Tips for HCG Injections Learning to give yourself HCG injections is a big step in your treatment