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Description
This is nearing the levels obtained by bariatric surgery

Semaglutide has a half-life of approximately seven days, which means weekly dosing maintains relatively steady concentrations

As a subcutaneously injected peptide, its bioavailability is not affected by food intake at the time of injection

In the intramuscular treatment arm, vitamin B12 will be administered as follows: 1 mg on alternate days in weeks 1 and 2, 1 mg/week in weeks 38,and 1 mg/month in weeks 952
