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60,61 Moreover, MPO levels are elevated during exacerbations of COPD

Choi SM, Lee KM, Ryu SB, Park YJ, Hwang YG, Baek D, Choi Y, Park KH, Park KD, Lee JW

Hydroxocobalamine (Sigma-Aldrich, Germany), Ethylenediaminetetraacetic acid (EDTA), propylene glycol (PG), polyethylenglycole (PEG 400), sorbitan mono oleate and buffering agents (Citrate, Acetate and Phosphate) were provided by Merck- Schuchardt, Hohenbrunn, Germany

Although the incidence is lower than other more common irAEs, it has a poor prognosis and often results in delay or discontinuation of ICIs
