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Here, we demonstrated that preferential accumulation of peroxidized phospholipids and loss of the antioxidant enzyme glutathione peroxidase 4 (GPX4) were responsible for vulnerability of midbrain dopaminergic neurons and progressive motor dysfunctions in a mouse model of PD

Cytosolic glutathione S -transferases (GSTs) are a superfamily of enzymes that protect normal cells by catalyzing conjugation reactions of electrophilic compounds, including carcinogens, to glutathione

It is widely studied in biochemical and cellular research due to its role in intracellular redox processes and thiol-based molecular interactions

Energy restriction and the risk of spontaneous mammary tumors in mice: a meta-analysis