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Although, some proteins and molecules showed its distinct characteristics in the progress, they almost remained in a cell or mouse model without the support of human experiments

For bacterial communities, the 16S ribosomal RNA (rRNA) gene is targeted, as it is highly conserved across all bacteria, with variable regions allowing for species differentiation [86]

Spatiotemporal immune zonation of the human kidney

These interactions highlight the ability of polyphenols to simultaneously address multiple pathological mechanisms in AD, including oxidative stress, neuroinflammation, and neurodegeneration, underscoring their potential as multitarget therapeutic agents for AD