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Several mutations have been described [21, 22, 25, 26, 29, 3133]

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Este hecho qued reflejado en el estudio Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake donde se redujo la glucosa plsmatica, disminuy la resistencia a la insulina (recordemos que una buena sensibilidad a la insulina previene la diabetes y produce una ganancia de msculo ms limpia con menos grasa) e incluso mejor la resistencia al estrs preveniendo lesiones neuronales