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Mechanisms involved are thought to include tracheal microaspiration of acid stimulating bronchospasm 30 and increased airway hyper-reactivity associated with acid reflux into the lower esophagus

Zhang Y, Chen S, Wei J, Jiang J, Lin X, Wang Y, Hao C, Wu W, Yuan Z, Sun J, et al

Nervous system and stress tolerance B12 deficiency doesn't just affect mood directly it degrades your capacity to handle stress