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demonstrated that rabbit hemorrhagic disease virus (RHDV) infection induces NF-B activation, and Keap1 interaction reduces Nrf2-related antioxidant function 136

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It has been reported that the protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges

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