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Report of an interdisciplinary conference and review

1) suggests a pressing need for more advanced cartilage repair technologies that might obviate the need for TKA and control the high socio-economic burden of end-stage knee arthritis

Int J Mol Sci 23(5):2894

When assessed using Relational database of Metabolomic Pathways (RaMP-DB) that has 3694 metabolite and lipid pathways integrated from KEGG, HMDB, Reactome and WikiPathways, the significant pathways were Oligodendrocyte specification and differentiation leading to myelin components for CNS, Immunoregulatory interactions between lymphoid and non-lymphoid cells, Kennedy pathway from sphingolipids, MTHFR deficiency, Sphingolipid pathway and Glycerolipids and glycerophospholipids