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smegmatis sliding have used the agarose based motility assay that generates round colonies (Recht et al ., 2000

47 AGEs increase oxidative stress and inflammation, cause widespread cellular dysfunction, and may damage signaling pathways related to reproductive function

Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis

The UK study placed great weight on the risk for acute physical harm, the propensity for physical and psychological dependency on the drug, and the negative familial and societal impacts of the drug