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In: Gvozdjkov A, Cornlissen G, Singh RB (eds), Recent advances in mitochondrial diseases and coenzyme Q 10 , NOVA Sciences, USA, pp 7179 Editor information Editors and Affiliations Rights and permissions Copyright information 2024 The Author(s), under exclusive license to Springer Nature Switzerland AG About this chapter Cite this chapter Gvozdjkov, A
Melatonin Inhibits Ferroptosis and Delays Age-Related Cataract by Regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 Pathways
The main use of injectable glutathione is skin whitening, which raises real ethical concerns rooted in colourism and racist beauty standards
Activation of the SIRT1/Nrf2 pathway, such as by alpha lipoic acid, can modulate iron metabolism and mitigate ferroptosis by up-regulating ferritin and ferritin heavy chain 1 (FTH1), and down-regulating the iron import protein divalent metal transporter 1 (DMT1) (Zheng et al., 2023)
