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Description
L-carnitine treatment in incident hemodialysis patients: the multicenter, randomized, double-blinded, placebo-controlled CARNIDIAL trial

Kraemer WJ, Spiering BA, Volek JS, Ratamess NA, Sharman MJ, Rubin MR, French DN, Silvestre R, Hatfield DL, Van Heest JL, Vingren JL, Judelson DA, Deschenes MR, Maresh CM

doi: 10.1038/s41591-018-0128-1

Furthermore, administration of L-carnitine substantially altered the effects of TRZ and markedly reduced the expression of autophagy-related genes such as Beclin1, Autophagy Related Gene 5 (ATG5), and the inflammatory mediator TNF- in comparison to the TRZ treated group (Khedr et al