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doi:10.7150/ijbs.81892 This issue Cite Review 1
The Leu/Pro polymorphism (at SNP rs1050450, commonly referred to as Pro198Leu) shows an interesting geneenvironment effect in that these allelic forms differ in their expression in response to selenium

By restoring NAD+ where NNMT had been depleting it, 5-Amino-1MQ aims to flip stubborn, storage-mode fat cells back toward an active, energy-burning state

Egger NG, Anderson KE, Lindenbaum J, et al
