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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Boord JB, Maeda K, Makowski L, Babaev VR, Fazio S, Linton MF, Hotamisligil GS

Maintenance of efficacy for patients treated with VYVANSE was demonstrated by the significantly lower proportion of patients with treatment failure (9%) compared to patients receiving placebo (75%) at endpoint during the double-blind phase (Study 9, Figure 7)

SST2 serves as an inflammation marker and indicator of myocardial stress, and it dampens the cardioprotective effects of transmembrane binding receptor suppression of tumorigenicity 2 (ST2L) via the myeloid differentiation primary response 88 (MyD88)/IRAK/ERK/NF-B signaling pathway by competing with IL-33 (Kakkar and Lee, 2008)

International Journal of Molecular Sciences