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Description
Depletion of phospholipid hydroperoxide glutathione peroxidase up-regulates arachidonate metabolism by 12S-lipoxygenase and cyclooxygenase 1 in human epidermoid carcinoma A431 cells
Oxidized glutathione bound to another glutathione molecule
Subsequently, infiltrating inflammatory mediators and immune cells can trigger reactive activation of microglia and astrocytes, promoting further inflammatory signaling within the CNS and thereby sustaining a neuroinflammatory microenvironment (Linnerbauer et al., 2020
10.1248/bpb.28.1311 230 RadwanM
