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Description
Oxidative and inflammatory processes may affect a plaques lipid content, immune-cell activity, fibrous covering, and vulnerability to rupture

Cycled therapy is common

developed a model of Ox-LDL-induced ferroptosis in HUVECs, showing that CTRP13 intervention increased antioxidant enzyme expression, preventing AS and protecting endothelial cells from ferroptosis ( / mice by reducing mitochondrial damage, boosting glutathione and superoxide dismutase levels, and decreasing LPO and MDA levels

Studies comparing 8-OHdG levels in the urine of AD patients and healthy controls have demonstrated positive correlations between 8-OHdG levels and dermatitis scores, indicating disease severity
