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ACT-AD Phase 2 Trial Fosgonimeton's Phase 2 ACT-AD trial in Alzheimer's patients fails its primary endpoint
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Common issues include nausea, diarrhea, abdominal pain, and vomiting, which are typical of GLP-1 agonists
Anti-inflammatory and cytoprotective effects were noted in a systematic review in 2024 and are also said to include attenuating oxidative stress and reinforcing gastrointestinal mucosal barriers during experimental injury
