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Scientific References Sikiric P, et al

The mechanism involves upregulation of VEGF expression a key growth factor in new blood vessel formation and activation of ERK1/2 signaling pathways that drive cell proliferation, migration, and angiogenesis

Cell culture and peptide handling The HCC line HepG2 (American Type Culture Collection (ATCC) Manassas, VA, USA) was maintained in Dulbeccos modified Eagles media (DMEM) with 4.5 g/l glucose (Corning, Corning, NY), 10% fetal bovine serum (Corning), and 100 U/ml penicillin and streptomycin (Gibco)

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