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At the last follow-up visit (median 5 months, minimum 3 - maximum 39 months), 3 patients were still receiving immunoglobulin substitution: patient #2 received subcutaneous immunoglobulin, whereas patient #7 and patient #9 received monthly IVIg
Sample sizes (typically 36 biological replicates per group) were selected based on established standards in the field and our preliminary data, which indicated that this range was sufficient to detect biologically relevant effects
J Clin Biochem Nutr 69(1):7790
Metabolism as a tool for understanding human brain evolution: lipid energy metabolism as an example
