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For tirzepatide, typical dosing begins at 2.5 mg once weekly, with gradual increases up to 15 mg weekly depending on patient response

We list some pointel aspects for future research as following: (1) More appropriate in vitro and in vivo models for evaluation of BBB permeability
[7] [9] As with all parenteral medications, administration should be avoided in the presence of local or systemic infection at the injection site

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