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At this usually very early stage (infancy), the parents decide on the therapeutic approach for their child
Reduce the dose by 0.5mg on the next administration
Interestingly, overexpression of the c-KIT tyrosine kinase, a key regulator of melanocytes, has been described in a great number of mucosal melanoma cases (from 39 to 88% depending on the study) and could be a marker or even a target for KIT inhibitors for the treatment of metastatic mucosal melanomas [3, 31]
