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Studies give extremely different results some show that high levels of IGF-1 in the elderly increase the risk of dementia, other that low levels of IGF-1 increase this risk
doi: 10.1016/j.freeradbiomed.2007.01.024
Alternative Start Sites in the Saccharomyces cerevisiae GLR1 Gene Are Responsible for Mitochondrial and Cytosolic Isoforms of Glutathione Reductase
The pulse it produces is sharp but brief, which is the single biggest practical limitation compared to modern alternatives
