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Limited ability to block infections What has become clear is that first-generation vaccines are somewhat limited in their ability to prevent infections, with an efficacy of ~75% for preventing symptomatic infections but only ~45% for preventing asymptomatic infections [5]

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doi: 10.1182/bloodadvances.2023010822 102 El-MasriBMLekaBMustaphaFGundesenMTHingeMLundTet al