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Activation of AMPK by metformin and 5-aminomidazole-4-carboxamide ribonucleotide (AICAR) mimics stress-like cellular responses and leads to the translocation of MOTS-c to the nucleus (Fig

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GSB-106 activates all three major TrkB signaling pathways: MAPK/ERK, PI3K/AKT, and PLCgamma

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