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The critical roles of polyamines in regulating ColE7 production and restricting ColE7 uptake of the colicin-producing Escherichia coli

Although IV and oral acetylcysteine are equally effective for this indication, oral administration is generally poorly tolerated due to the higher dosing required to overcome its low oral bioavailability, [26] its foul taste and odor, and a higher incidence of adverse effects when taken orally, particularly nausea and vomiting

doi: 10.1016/j.biotechadv.2016.08.003 54 LiM.YangD.MeiL.YuanL.XieA.YuanJ.et al

Liu N, Xu X (2012) Neuroprotection and its molecular mechanism following spinal cord injury