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Description
Riboflavin-specific transporters are found on the outer membrane of the mitochondria
Isik et al., 2023)
In contrast to previous studies, our meta-analysis focused on the use of AOX in general, and not on specific molecules or combinations, for which the studies are very heterogenous
In fact, DNA methylation has been described in many studies involving tamoxifen resistance, identifying two main mechanisms of resistance: downregulation of estrogen receptor (ER) expression and abnormal activation of the PI3K/AKT/mTOR (mammalian target of rapamycin) signaling pathway [149]
