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Osteoporosis involves a gradual decline in osteoblasts and increased bone resorption by osteoclasts
10.1503/cmaj.140339 69 LestnerJ
The tripeptide exists intracellularly either in an oxidised glutathione disulphide (GSSG) or reduced state (GSH), and maintaining an optimal GSH:GSSG ratio in the cell is critical for prevention of oxidative damage and for cell survival (Fig
El-Dessouki AM, Alzokaky AA, Raslan NA, Ibrahim S, Selim H, Al-Karmalawy AA (2025) Dabigatran attenuates methotrexate-induced hepatotoxicity by regulating coagulation, endothelial dysfunction, and the NF-kB/IL-1beta/MCP-1 and TLR4/NLRP3 signaling pathways
