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Such multi-omics approaches will be central to understanding how to restore skin homeostasis and to translating basic research into clinical applications

Cell Host Microbe 28 , 89103 (2020)

Discovery, synthesis, and structure-based optimization of a series of N -( tert -butyl)-2-( N -arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease

They open at the strategic level, prove capabilities operationally, then climb back up to reinforce the value
