glutathione fluorophore Green: spectra (a) absorbance and (b) fluorescence, (c) A locally activatable sensor for

Licorice extract contains the active component glabridin, which suppresses melanin formation, resulting in lighter skin and less hyperpigmentation

Differently from GSH, which enters the cells directly, SAG is more stable in blood plasma and, once entered into cell cytoplasm, is converted by cytoplasmatic thioesterases to GSH

The compound also decreased the activity of stress-induced kinases (SAPK/JNK and pERK1/2), suggesting additional neuroprotective mechanisms beyond simple neurotrophin upregulation

Given its important role in maintaining homeostasis, any disruption in thyroid function can have far-reaching consequences, manifesting as a spectrum of disorders ranging from hypothyroidism to hyperthyroidism and thyroid cancer