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Curcumin may demethylate tumor-suppressor genes in cancer cells but also suppress inflammatory-gene promoters in immune cells, reflecting tissue-specific signaling crosstalk rather than a uniform epigenetic mechanism (Reuter et al., 2011)

Never combine DSIP with prescription sleep medications without medical supervision

doi: 10.1210/me.2015-1122 156 CottrellJNWitcherACComleyKCunninghamMWJrIbrahimTCorneliusDCet al

V.JohnsenS.RasheedS.MakimuraH.LeeH.et al (2011)