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It sold a total of 1,646,630 copies, making it a massive hit (a #1 single in Japan) and their highest selling single

However, RNAi therapeutics still face technical obstacles, such as achieving efficient delivery of RNAi drugs targeting organs or tissues and overcoming the off-target interactions (Persengiev et al., 2004

Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues

doi: 10.1073/pnas.0912306107 12 MesquitaFSAbramiLLinderMEBamjiSXDickinsonBCvan der GootFG
