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Conversely, isoniazid and pyrazinamide (tuberculosis drugs) are structural analogs of niacin that can interfere with niacin metabolism, potentially precipitating pellagra in rare cases
its activity is diminished in cellular assays owing to its swift degradation to adenosine and Hcy by SAH hydrolase ( Streptomyces , serves as a SAM-mimicking methyltransferase inhibitor
For finer dose control, add 3 mL instead of 2 mL, producing a 3.33 mg/mL concentration
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