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Diabetes Care 30:28802885 Biesemann N, Ried JS, Ding-Pfennigdorff D et al (2018) High throughput screening of mitochondrial bioenergetics in human differentiated myotubes identifies novel enhancers of muscle performance in aged mice
However, additional products of the mevalonate pathway, such as geranylgeranyl, likely contribute to inhibiting the Hippo signaling pathway and increasing YAP translocation via posttranslational modifications
These byproducts are subsequently detoxified by glutathione peroxidase, further contributing to cellular redox balance
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