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Description
Studies that used 1 mg/day in oral and intravenous trials did not show meaningfully better outcomes than lower doses, and higher doses were associated with more reports of headache, diarrhea, and gastrointestinal effects

This is exploratory territory if you go higher, do it with bloodwork monitoring and go slowly

Weight loss results may vary among individuals depending on body mass index, genetics, lifestyle, dietary habits, and physical activity

Orthopaedic journal of sports medicine, 6(10), 2325967118804544